:   Ѵٸ ϡ
ڸ dzϸ鼭 Įθ ǰ ̿뿡 Ϸ θ ˷ ִ. ڸ Ÿ C 濡 ָ, ݶ Ǻ .׷ ڸ ߸ ϸ 츮 ִ. Ư ؾ Ѵ. ڸ Ǫ(Furanocoumarin) Ư ๰ ȣ ۿϿ ɰ ۿ ų ֱ .







ڸ ๰

츮 ü ???輳 ģ. ũ P450 3A4 (CYP3A4) 翡 ϴ ȿҷ, ü ๰ ϰ ռϿ ȿ Ÿ Ѵ. ڸ Ǫ CYP3A4 ۿ Ѵ. Ǫ CYP3A4 ๰ ۿ Ǹ ๰ صǰ ʾ ๰ 󵵰 Ѵ. ̷ ȿ ġ ǰ ִ.̴ ̼ о ڸֽ Բ , ๰󵵸 ִ ۿ ʷ ִ١ ߴ. ̴ а ǻ ֿö (̿ǿ) ̴ Q&A "ڸ ๰ ȣ ־ ӵ ߸, ü Ǵ ȿ ׸ŭ ۿ ɼ δ" ߴ. ڸ ๰ ۿ뿡 ұĢ ڵ, ȣ , ̸ ִ. 



ڸ Բ Ǵ

2012 ij ȸ(Canadian Medical Association Journal) ڸ ȣۿϴ ๰ 85 . ɰ ۿ ʷ ִ 43 Ʒ . ๰ ڸ Ծ ġ ȣۿ Ÿ Ƿ Ư ؾ Ѵ.1. (Anti-Lipemic Agents) : 丣ٽƾ(Atorvastatin), ιٽŸƾ(Lovastatin), ɹٽŸƾ(Simvastatin)2. װ(Anti-Infective Agents) : Ʈθ̽(Erythromycin), ҷƮ(Halofantrine), (Praziquantel), (Primaquine), ϳ(Quinine), Ǻ(Rilpivirine)3. ׾(Anti-Cancer Agents) : ũƼ(Crizotinib), ٽƼ(Dasatinib), Ƽ(Erlotinib), θ(Everolimus), Ƽ(Lapatinib), ҷƼ(Nilotinib), Ĵ(Pazopanib), ݵŸ(Vandetanib), 糪(Venurafenib)4. (Cardiovascular Agents) : ƹ̿ٷ(Amiodarone), Ȼ(Apixaban), ǷνŸ(Cilostazol), Ŭǵ׷(Clopidogrel), γ״ٷ(Dronedarone), ÷(Eplerenone), Ÿ(Ergotamine), Ƽī׷(Ticagrelor), Ĺ(Verapamil)5. ŽŰ (CNS Agents) : Ÿ(Alfentanil ? oral), νǷ(Buspirone), 丣丣(Dextromethorphan), Ÿ(Fentanyl ? oral), Ÿ(Ketamine ? oral), õ(Lurasidone), ڵ(Oxycodone), Ǹ(Pimozide), Ƽ(Quetiapine), õ(Ziprasidone)6. (Gastrointestinal Agents) :û̵(cisapride), 丮(domperidone)7. 鿪(Immunosuppressant Agents) :Ŭν(Cyclosporine), θ(Everolimus), ĸ̽(Sirolimus), Ÿũθ(Tacrolimus)

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